Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cdh1  cadherin 1   (Synonyms: Ecad, E-cad, E-cadherin, L-CAM, UM, uvomorulin)
Results	Reference
1	J:220460 Andre P, Song H, Kim W, Kispert A, Yang Y, Wnt5a and Wnt11 regulate mammalian anterior-posterior axis elongation. Development. 2015 Apr 15;142(8):1516-27
1	J:131055 Arnold SJ, Hofmann UK, Bikoff EK, Robertson EJ, Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse. Development. 2008 Feb;135(3):501-11
1	J:253960 Basilicata MF, Frank M, Solter D, Brabletz T, Stemmler MP, Inappropriate cadherin switching in the mouse epiblast compromises proper signaling between the epiblast and the extraembryonic ectoderm during gastrulation. Sci Rep. 2016 May 24;6:26562
1	J:251816 Bazzi H, Soroka E, Alcorn HL, Anderson KV, STRIP1, a core component of STRIPAK complexes, is essential for normal mesoderm migration in the mouse embryo. Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):E10928-E10936
1*	J:329966 Bell CJ, Gupta N, Tremblay KD, Mager J, Borcs6 is required for endo-lysosomal degradation during early development. Mol Reprod Dev. 2022 Aug;89(8):337-350
1	J:254597 Bhargava S, Cox B, Polydorou C, Gresakova V, Korinek V, Strnad H, Sedlacek R, Epp TA, Chawengsaksophak K, The epigenetic modifier Fam208a is required to maintain epiblast cell fitness. Sci Rep. 2017 Aug 24;7(1):9322
1	J:183946 Bloomekatz J, Grego-Bessa J, Migeotte I, Anderson KV, Pten regulates collective cell migration during specification of the anterior-posterior axis of the mouse embryo. Dev Biol. 2012 Apr 15;364(2):192-201
1	J:72861 Carver EA, Jiang R, Lan Y, Oram KF, Gridley T, The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition. Mol Cell Biol. 2001 Dec;21(23):8184-8
1*	J:290315 Cheong A, Archambault D, Degani R, Iverson E, Tremblay KD, Mager J, Nuclear-encoded mitochondrial ribosomal proteins are required to initiate gastrulation. Development. 2020 May 26;147(10):dev188714
1*	J:278736 Cheong A, Degani R, Tremblay KD, Mager J, A null allele of Dnaaf2 displays embryonic lethality and mimics human ciliary dyskinesia. Hum Mol Genet. 2019 Aug 15;28(16):2775-2784
1*	J:70485 Ciruna B, Rossant J, FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak. Dev Cell. 2001;1(1):37-49
1	J:171148 Daane JM, Enders AC, Downs KM, Mesothelium of the murine allantois exhibits distinct regional properties. J Morphol. 2011 May;272(5):536-56
1*	J:165751 Du J, Takeuchi H, Leonhard-Melief C, Shroyer KR, Dlugosz M, Haltiwanger RS, Holdener BC, O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation. Dev Biol. 2010 Oct 1;346(1):25-38
1	J:198627 Engert S, Burtscher I, Liao WP, Dulev S, Schotta G, Lickert H, Wnt/beta-catenin signalling regulates Sox17 expression and is essential for organizer and endoderm formation in the mouse. Development. 2013 Aug;140(15):3128-38
1	J:139139 Garcia-Garcia MJ, Shibata M, Anderson KV, Chato, a KRAB zinc-finger protein, regulates convergent extension in the mouse embryo. Development. 2008 Sep;135(18):3053-62
1	J:147283 Gu Y, Runyan C, Shoemaker A, Surani A, Wylie C, Steel factor controls primordial germ cell survival and motility from the time of their specification in the allantois, and provides a continuous niche throughout their migration. Development. 2009 Apr;136(8):1295-303
1*	J:336449 Haerlingen B, Opitz R, Vandernoot I, Molinaro A, Shankar MP, Gillotay P, Trubiroha A, Costagliola S, Mesodermal FGF and BMP govern the sequential stages of zebrafish thyroid specification. Development. 2023 May 15;150(10)
1	J:149220 Hara K, Kanai-Azuma M, Uemura M, Shitara H, Taya C, Yonekawa H, Kawakami H, Tsunekawa N, Kurohmaru M, Kanai Y, Evidence for crucial role of hindgut expansion in directing proper migration of primordial germ cells in mouse early embryogenesis. Dev Biol. 2009 Jun 15;330(2):427-39
1	J:279070 Hernandez-Martinez R, Ramkumar N, Anderson KV, p120-catenin regulates WNT signaling and EMT in the mouse embryo. Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):16872-16881
1	J:137938 Herranz N, Pasini D, Diaz VM, Franci C, Gutierrez A, Dave N, Escriva M, Hernandez-Munoz I, Di Croce L, Helin K, Garcia de Herreros A, Peiro S, Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor. Mol Cell Biol. 2008 Aug;28(15):4772-81
1	J:142596 Hirano M, Hashimoto S, Yonemura S, Sabe H, Aizawa S, EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial-mesenchymal transition. J Cell Biol. 2008 Sep 22;182(6):1217-30
1	J:195125 Hoffman JA, Wu CI, Merrill BJ, Tcf7l1 prepares epiblast cells in the gastrulating mouse embryo for lineage specification. Development. 2013 Apr;140(8):1665-75
1	J:57589 Ikeda W, Nakanishi H, Miyoshi J, Mandai K, Ishizaki H, Tanaka M, Togawa A, Takahashi K, Nishioka H, Yoshida H, Mizoguchi A, Nishikawa S, Takai Y, Afadin: A key molecule essential for structural organization of cell-cell junctions of polarized epithelia during embryogenesis. J Cell Biol. 1999 Sep 6;146(5):1117-32
1	J:327957 Kim YS, Fan R, Lith SC, Dicke AK, Drexler HCA, Kremer L, Kuempel-Rink N, Hekking L, Stehling M, Bedzhov I, Rap1 controls epiblast morphogenesis in sync with the pluripotency states transition. Dev Cell. 2022 Aug 22;57(16):1937-1956.e8
1	J:244157 Lange L, Marks M, Liu J, Wittler L, Bauer H, Piehl S, Blass G, Timmermann B, Herrmann BG, Patterning and gastrulation defects caused by the tw18 lethal are due to loss of Ppp2r1a. Biol Open. 2017 Jun 15;6(6):752-764
1	J:165744 Lee JD, Migeotte I, Anderson KV, Left-right patterning in the mouse requires Epb4.1l5-dependent morphogenesis of the node and midline. Dev Biol. 2010 Oct 15;346(2):237-46
1*	J:122548 Lee JD, Silva-Gagliardi NF, Tepass U, McGlade CJ, Anderson KV, The FERM protein Epb4.1l5 is required for organization of the neural plate and for the epithelial-mesenchymal transition at the primitive streak of the mouse embryo. Development. 2007 Jun;134(11):2007-16
1*	J:90402 Merrill BJ, Pasolli HA, Polak L, Rendl M, Garcia-Garcia MJ, Anderson KV, Fuchs E, Tcf3: a transcriptional regulator of axis induction in the early embryo. Development. 2004 Jan;131(2):263-74
1	J:173526 Migeotte I, Grego-Bessa J, Anderson KV, Rac1 mediates morphogenetic responses to intercellular signals in the gastrulating mouse embryo. Development. 2011 Jul;138(14):3011-20
1	J:258132 Morgani SM, Metzger JJ, Nichols J, Siggia ED, Hadjantonakis AK, Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning. Elife. 2018 Feb 7;7:e32839
1	J:308051 Morgani SM, Su J, Nichols J, Massague J, Hadjantonakis AK, The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos. Elife. 2021 Apr 30;10:e64811
1*	J:195277 Nakamura H, Cook RN, Justice MJ, Mouse Tenm4 is required for mesoderm induction. BMC Dev Biol. 2013;13:9
1	J:90052 Okabe N, Ozaki-Kuroda K, Nakanishi H, Shimizu K, Takai Y, Expression patterns of nectins and afadin during epithelial remodeling in the mouse embryo. Dev Dyn. 2004 May;230(1):174-86
1	J:198710 Plaks V, Rinkenberger J, Dai J, Flannery M, Sund M, Kanasaki K, Ni W, Kalluri R, Werb Z, Matrix metalloproteinase-9 deficiency phenocopies features of preeclampsia and intrauterine growth restriction. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11109-14
1	J:157256 Powers SE, Taniguchi K, Yen W, Melhuish TA, Shen J, Walsh CA, Sutherland AE, Wotton D, Tgif1 and Tgif2 regulate Nodal signaling and are required for gastrulation. Development. 2010 Jan;137(2):249-59
1	J:171894 Qian L, Mahaffey JP, Alcorn HL, Anderson KV, Tissue-specific roles of Axin2 in the inhibition and activation of Wnt signaling in the mouse embryo. Proc Natl Acad Sci U S A. 2011 May 24;108(21):8692-7
1	J:119028 Rakeman AS, Anderson KV, Axis specification and morphogenesis in the mouse embryo require Nap1, a regulator of WAVE-mediated actin branching. Development. 2006 Aug;133(16):3075-83
1	J:227336 Ramkumar N, Harvey BM, Lee JD, Alcorn HL, Silva-Gagliardi NF, McGlade CJ, Bestor TH, Wijnholds J, Haltiwanger RS, Anderson KV, Protein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2. PLoS Genet. 2015 Oct;11(10):e1005551
1	J:184873 Rhee JM, Iannaccone PM, Mapping mouse hemangioblast maturation from headfold stages. Dev Biol. 2012 May 1;365(1):1-13
1	J:166040 Rocha PP, Scholze M, Bleiss W, Schrewe H, Med12 is essential for early mouse development and for canonical Wnt and Wnt/PCP signaling. Development. 2010 Aug;137(16):2723-31
1*	J:143782 Schmidt S, Hommel A, Gawlik V, Augustin R, Junicke N, Florian S, Richter M, Walther DJ, Montag D, Joost HG, Schurmann A, Essential role of glucose transporter GLUT3 for post-implantation embryonic development. J Endocrinol. 2009 Jan;200(1):23-33
1	J:202124 Seidl S, Braun U, Roos N, Li S, Ludtke TH, Kispert A, Leitges M, Phenotypical analysis of atypical PKCs in vivo function display a compensatory system at mouse embryonic day 7.5. PLoS One. 2013;8(5):e62756
1	J:275024 Senft AD, Bikoff EK, Robertson EJ, Costello I, Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development in mouse. Nat Commun. 2019 Mar 6;10(1):1089
1	J:34424 Slager HG, Lawson KA, van den Eijnden-van Raaij AJ, de Laat SW, Mummery CL, Differential localization of TGF-beta 2 in mouse preimplantation and early postimplantation development. Dev Biol. 1991 Jun;145(2):205-18
1*	J:343201 Srinivasan S, He X, Mirza S, Mager J, Exosome complex components 1 and 2 are vital for early mammalian development. Gene Expr Patterns. 2023 Nov 7;51:119346
1*	J:93477 Takito J, Al-Awqati Q, Conversion of ES cells to columnar epithelia by hensin and to squamous epithelia by laminin. J Cell Biol. 2004 Oct 27;166(7):1093-102
1*	J:277394 Tellier AP, Archambault D, Tremblay KD, Mager J, The elongation factor Elof1 is required for mammalian gastrulation. PLoS One. 2019;14(7):e0219410
1*	J:186556 Trask MC, Tremblay KD, Mager J, Yin-Yang1 is required for epithelial-to-mesenchymal transition and regulation of Nodal signaling during mammalian gastrulation. Dev Biol. 2012 Aug 15;368(2):273-82
1*	J:231877 Vestweber D, Kemler R, Rabbit antiserum against a purified surface glycoprotein decompacts mouse preimplantation embryos and reacts with specific adult tissues. Exp Cell Res. 1984 May;152(1):169-78
1	J:166759 Villasenor A, Chong DC, Henkemeyer M, Cleaver O, Epithelial dynamics of pancreatic branching morphogenesis. Development. 2010 Dec;137(24):4295-305
1	J:223874 Viotti M, Nowotschin S, Hadjantonakis AK, SOX17 links gut endoderm morphogenesis and germ layer segregation. Nat Cell Biol. 2014 Dec;16(12):1146-56
1	J:325905 Willnow D, Benary U, Margineanu A, Vignola ML, Konrath F, Pongrac IM, Karimaddini Z, Vigilante A, Wolf J, Spagnoli FM, Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche. Nature. 2021 Sep;597(7874):87-91
1	J:227708 Wiszniak S, Scherer M, Ramshaw H, Schwarz Q, Neuropilin-2 genomic elements drive cre recombinase expression in primitive blood, vascular and neuronal lineages. Genesis. 2015 Nov;53(11):709-17
1	J:132649 Xu J, Kausalya PJ, Phua DC, Ali SM, Hossain Z, Hunziker W, Early embryonic lethality of mice lacking ZO-2, but Not ZO-3, reveals critical and nonredundant roles for individual zonula occludens proteins in mammalian development. Mol Cell Biol. 2008 Mar;28(5):1669-78
1	J:130469 Yamanaka Y, Tamplin OJ, Beckers A, Gossler A, Rossant J, Live imaging and genetic analysis of mouse notochord formation reveals regional morphogenetic mechanisms. Dev Cell. 2007 Dec;13(6):884-96
1	J:317371 Zhang Y, Liu C, Adelstein RS, Ma X, Replacing nonmuscle myosin 2A with myosin 2C1 permits gastrulation but not placenta vascular development in mice. Mol Biol Cell. 2018 Sep 15;29(19):2326-2335
1	J:106348 Zohn IE, Li Y, Skolnik EY, Anderson KV, Han J, Niswander L, p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation. Cell. 2006 Jun 2;125(5):957-69